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Target
Sentrin-specific protease 8
Ligand
BDBM49383
Substrate
n/a
Meas. Tech.
SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2
IC50
1080±n/a nM
Citation
 PubChem, PC SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2 PubChem Bioassay (2011)[AID]
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM49383
Synonyms:
Furan-2-carboxylic acid (6-chloro-benzothiazol-2-yl)-amide | MLS000528609 | N-(6-chloranyl-1,3-benzothiazol-2-yl)furan-2-carboxamide | N-(6-chloro-1,3-benzothiazol-2-yl)-2-furamide | N-(6-chloro-1,3-benzothiazol-2-yl)-2-furancarboxamide | N-(6-chloro-1,3-benzothiazol-2-yl)furan-2-carboxamide | SMR000118184 | cid_3143005
Type:
Small organic molecule
Emp. Form.:
C12H7ClN2O2S
Mol. Mass.:
278.714
SMILES:
Clc1ccc2nc(NC(=O)c3ccco3)sc2c1
Structure:
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