Reaction Details  Report a problem with these data
Target
Sentrin-specific protease 8
Ligand
BDBM84056
Substrate
n/a
Meas. Tech.
SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2
IC50
40800±n/a nM
Citation
 PubChem, PC SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2 PubChem Bioassay (2011)[AID]
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM84056
Synonyms:
MLS-0454610.0002 | N'-[(Z)-3-indolylidenemethyl]-2-thiophenecarbohydrazide | N'-[(Z)-indol-3-ylidenemethyl]thiophene-2-carbohydrazide | cid_5403822
Type:
Small organic molecule
Emp. Form.:
C14H11N3OS
Mol. Mass.:
269.322
SMILES:
O=C(NN=Cc1c[nH]c2ccccc12)c1cccs1 |w:3.2|
Structure:
Search PDB for entries with ligand similarity: