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Target
Sentrin-specific protease 8
Ligand
BDBM84079
Substrate
n/a
Meas. Tech.
SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2
IC50
84000±n/a nM
Citation
 PubChem, PC SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2 PubChem Bioassay (2011)[AID]
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM84079
Synonyms:
MLS-0454652.0002 | N-[2-[[2-(4-fluorophenyl)-1H-indol-3-yl]sulfinyl]ethyl]-2-(1H-indol-3-yl)-2-keto-acetamide | N-[2-[[2-(4-fluorophenyl)-1H-indol-3-yl]sulfinyl]ethyl]-2-(1H-indol-3-yl)-2-oxidanylidene-ethanamide | N-[2-[[2-(4-fluorophenyl)-1H-indol-3-yl]sulfinyl]ethyl]-2-(1H-indol-3-yl)-2-oxoacetamide | cid_16815047
Type:
Small organic molecule
Emp. Form.:
C26H20FN3O3S
Mol. Mass.:
473.519
SMILES:
Fc1ccc(cc1)-c1[nH]c2ccccc2c1S(=O)CCNC(=O)C(=O)c1c[nH]c2ccccc12
Structure:
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