Reaction Details  Report a problem with these data
Target
Somatostatin receptor type 4
Ligand
BDBM50063819
Substrate
n/a
Ki
26±n/a nM
Comments
PDSP_380
Citation
 Raynor, K; O'Carroll, AM; Kong, H; Yasuda, K; Mahan, LC; Bell, GI; Reisine, T Characterization of cloned somatostatin receptors SSTR4 and SSTR5. Mol Pharmacol 44:385-92 (1993) [PubMed]
Target
Name:
Somatostatin receptor type 4
Synonyms:
SOMATOSTATIN SST4 | SSR4_RAT | Somatostatin receptor | Somatostatin receptor type 4 | Sstr4
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42096.84
Organism:
RAT
Description:
SOMATOSTATIN SST4 SSTR4 RAT::P30937
Residue:
384
Sequence:
MNTPATLPLGGEDTTWTPGINASWAPDEEEDAVRSDGTGTAGMVTIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASAAALRHWPFGAVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAVFADTRPARGGEAVACNLHWPHPAWSAVFVIYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVTVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRSFQRVLCLRCCLLETTGGAEEEPLDYYATALKSRGGPGCICPPLPCQQEPMQAEPACKRVPFTKTTTF
  
Inhibitor
Name:
BDBM50063819
Synonyms:
BIM 23050 | CHEMBL413535 | cyclo[NMeDAla-Tyr-DTrp-Lys-Val-Phe]
Type:
Small organic molecule
Emp. Form.:
C44H56N8O7
Mol. Mass.:
808.9648
SMILES:
CC(C)[C@@H]1NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)N(C)C(=O)[C@@H](Cc2ccccc2)NC1=O
Structure:
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