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Target
Carbonic anhydrase 1
Ligand
BDBM50380144
Substrate
n/a
Meas. Tech.
ChEMBL_1673906 (CHEMBL4023935)
Kd
0.038±n/a nM
Citation
 Linkuvien?, V; Talibov, VO; Danielson, UH; Matulis, D Introduction of Intrinsic Kinetics of Protein-Ligand Interactions and Their Implications for Drug Design. J Med Chem 61:2292-2302 (2018) [PubMed]  Article
Target
Name:
Carbonic anhydrase 1
Synonyms:
4.2.1.1 | CA-I | CA1 | CAH1_HORSE | Carbonate dehydratase I | Carbonic anhydrase 1 | Carbonic anhydrase I
Type:
PROTEIN
Mol. Mass.:
28898.91
Organism:
Equus caballus
Description:
ChEMBL_117560
Residue:
260
Sequence:
MAHSDWGYDSPNGPEWVKLYPIANGNNQSPIDIKTSETKHDTSLKPFSVSYDPATAKEIVNVGHSFQVKFEDSDNRSVLKDGPLPGSYRLVQFHFHWGSTDDYGSEHTVDGVKYSAELHLVHWNSSKYSSFDEASSQADGLAILGVLMKVGEANPKLQKVLDALNEVKTKGKKAPFKNFDPSSLLPSSPDYWTYSGSLTHPPLYESVTWIVCKENISISSQQLSQFRSLLSNVEGGKAVPIQHNNRPPQPLKGRTVRAFF
  
Inhibitor
Name:
BDBM50380144
Synonyms:
CHEMBL2010994 | carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 8
Type:
Small organic molecule
Emp. Form.:
C16H19N3O4S2
Mol. Mass.:
381.47
SMILES:
CC(C)(C)c1cc(=O)[nH]c(SCC(=O)c2ccc(cc2)S(N)(=O)=O)n1
Structure:
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