Reaction Details  Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM50267794
Substrate
n/a
Meas. Tech.
ChEMBL_1703545 (CHEMBL4054778)
Ki
4500±n/a nM
Citation
 Stößel, A; Brox, R; Purkayastha, N; Hübner, H; Hocke, C; Prante, O; Gmeiner, P Development of molecular tools based on the dopamine D Bioorg Med Chem 25:3491-3499 (2017) [PubMed]  Article
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50267794
Synonyms:
CHEMBL4060837
Type:
Small organic molecule
Emp. Form.:
C31H37N5O5S
Mol. Mass.:
591.721
SMILES:
Cc1ccc(cc1)S([O-])(=O)=O.O=C(NCCCCN1CC[N+]2(CCOc3ccccc23)CC1)c1cc2ccccn2n1
Structure:
Search PDB for entries with ligand similarity: