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Target
D(1B) dopamine receptor
Ligand
BDBM50267795
Substrate
n/a
Meas. Tech.
ChEMBL_1703543 (CHEMBL4054776)
Ki
>10000±n/a nM
Citation
 Stößel, A; Brox, R; Purkayastha, N; Hübner, H; Hocke, C; Prante, O; Gmeiner, P Development of molecular tools based on the dopamine D Bioorg Med Chem 25:3491-3499 (2017) [PubMed]  Article
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM50267795
Synonyms:
CHEMBL4096858
Type:
Small organic molecule
Emp. Form.:
C26H32F3N5OS
Mol. Mass.:
519.625
SMILES:
CC(C)(C)c1nc(cc(n1)C(F)(F)F)N1CCN(CCCCNC(=O)c2cc3ccccc3s2)CC1
Structure:
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