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Target
Transcriptional enhancer factor TEF-3
Ligand
BDBM85507
Substrate
n/a
Meas. Tech.
ChEMBL_1710847 (CHEMBL4120896)
Kd
28000±n/a nM
Citation
 Gibault, F; Sturbaut, M; Bailly, F; Melnyk, P; Cotelle, P Targeting Transcriptional Enhanced Associate Domains (TEADs). J Med Chem 61:5057-5072 (2018) [PubMed]  Article
Target
Name:
Transcriptional enhancer factor TEF-3
Synonyms:
RTEF1 | TCF13L1 | TEA domain family member 4 | TEAD-4 | TEAD4 | TEAD4_HUMAN | TEF3 | Transcription factor 13-like 1 | Transcription factor RTEF-1 | Transcriptional enhancer factor TEF-3
Type:
PROTEIN
Mol. Mass.:
48333.01
Organism:
Homo sapiens
Description:
ChEMBL_118073
Residue:
434
Sequence:
MEGTAGTITSNEWSSPTSPEGSTASGGSQALDKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKAREIQAKLKDQAAKDKALQSMAAMSSAQIISATAFHSSMALARGPGRPAVSGFWQGALPGQAGTSHDVKPFSQQTYAVQPPLPLPGFESPAGPAPSPSAPPAPPWQGRSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGQSSPSYSDPYLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFLVKFWADLNTNIEDEGSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE
  
Inhibitor
Name:
BDBM85507
Synonyms:
CAS_4394-00-7 | NSC_4488 | Niflumic acid | Niflumic acid (Hit 16) | US10278929, Niflumic acid | US11337935, Compound Niflumic-acid | US20240002326, Compound Niflumic acid
Type:
Small organic molecule
Emp. Form.:
C13H9F3N2O2
Mol. Mass.:
282.218
SMILES:
OC(=O)c1cccnc1Nc1cccc(c1)C(F)(F)F
Structure:
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