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Target
D(2) dopamine receptor
Ligand
BDBM50305545
Substrate
n/a
Meas. Tech.
ChEMBL_1732881 (CHEMBL4148417)
Ki
534±n/a nM
Citation
 Kucwaj-Brysz, K; Kurczab, R; Jastrz?bska-Wi?sek, M; ?es?awska, E; Sata?a, G; Nitek, W; Partyka, A; Siwek, A; Jankowska, A; Weso?owska, A; Kie?-Kononowicz, K; Handzlik, J Computer-aided insights into receptor-ligand interaction for novel 5-arylhydantoin derivatives as serotonin 5-HT Eur J Med Chem 147:102-114 (2018) [PubMed]  Article
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50305545
Synonyms:
CHEMBL4162548
Type:
Small organic molecule
Emp. Form.:
C29H30ClN5O3
Mol. Mass.:
532.033
SMILES:
Cl.OC(CN1C(=O)NC(C1=O)(c1ccccc1)c1ccccc1)CN1CCN(CC1)c1ccccc1C#N
Structure:
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