Reaction Details  Report a problem with these data
Target
C-C chemokine receptor type 5
Ligand
BDBM50306034
Substrate
n/a
Meas. Tech.
ChEMBL_1732907 (CHEMBL4148443)
IC50
7.0±n/a nM
Citation
 Shah, HR; Savjani, JK Recent updates for designing CCR5 antagonists as anti-retroviral agents. Eur J Med Chem 147:115-129 (2018) [PubMed]  Article
Target
Name:
C-C chemokine receptor type 5
Synonyms:
C-C CKR-5 | C-C chemokine receptor type 5 | CC-CKR-5 | CCR-5 | CCR5 | CCR5/mu opioid receptor complex | CCR5_HUMAN | CD_antigen=CD195 | CHEMR13 | CMKBR5 | HIV-1 fusion coreceptor
Type:
Enzyme
Mol. Mass.:
40540.21
Organism:
Homo sapiens (Human)
Description:
P51681
Residue:
352
Sequence:
MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
  
Inhibitor
Name:
BDBM50306034
Synonyms:
CHEMBL4160473
Type:
Small organic molecule
Emp. Form.:
C6H12N2
Mol. Mass.:
112.1729
SMILES:
C1NCC2CNCC12
Structure:
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