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Target
D(2) dopamine receptor
Ligand
BDBM50017469
Substrate
n/a
Meas. Tech.
ChEMBL_59487 (CHEMBL670139)
Ki
4±n/a nM
Citation
 Craig, JC; Torkelson, SM; Findell, PR; Weiner, RI Synthesis and dopaminergic activity of 2-substituted octahydrobenzo[f]quinolines. J Med Chem 32:961-8 (1989) [PubMed]
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DRD2 | DRD2_BOVIN | Dopamine D2 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50698.79
Organism:
BOVINE
Description:
P20288
Residue:
444
Sequence:
MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50017469
Synonyms:
(9-Hydroxy-4-propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-2-yl)-acetonitrile | CHEMBL451557
Type:
Small organic molecule
Emp. Form.:
C18H24N2O
Mol. Mass.:
284.396
SMILES:
CCCN1C[C@H](CC#N)C[C@H]2[C@H]1CCc1ccc(O)cc21
Structure:
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