Reaction Details  Report a problem with these data
Target
Carbonic anhydrase 7
Ligand
BDBM50408245
Substrate
n/a
Meas. Tech.
ChEMBL_1739478 (CHEMBL4155228)
Ki
312±n/a nM
Citation
 Angeli, A; di Cesare Mannelli, L; Lucarini, E; Peat, TS; Ghelardini, C; Supuran, CT Design, synthesis and X-ray crystallography of selenides bearing benzenesulfonamide moiety with neuropathic pain modulating effects. Eur J Med Chem 154:210-219 (2018) [PubMed]  Article
Target
Name:
Carbonic anhydrase 7
Synonyms:
CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:
Enzyme
Mol. Mass.:
29664.11
Organism:
Homo sapiens (Human)
Description:
Human cloned isozyme.
Residue:
264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFRA
  
Inhibitor
Name:
BDBM50408245
Synonyms:
CHEMBL4175141
Type:
Small organic molecule
Emp. Form.:
C15H18N2O2SSe
Mol. Mass.:
369.34
SMILES:
[#6]-[#7](-[#6])-c1ccc([Se;v2][#6]-c2ccc(cc2)S([#7])(=O)=O)cc1
Structure:
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