Reaction Details  Report a problem with these data
Target
Sphingosine 1-phosphate receptor 5
Ligand
BDBM50453325
Substrate
n/a
Meas. Tech.
ChEMBL_1749910 (CHEMBL4184670)
EC50
20±n/a nM
Citation
  TBA Bioorg Med Chem Lett 28:459-465 (2018) [PubMed]  Article
Target
Name:
Sphingosine 1-phosphate receptor 5
Synonyms:
EDG8 | Endothelial differentiation sphingolipid G-protein-coupled receptor 8 | S1P5 | S1PR5 | S1PR5_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-8
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41796.42
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
398
Sequence:
MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALTASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLDACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRARRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSLLNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSFSGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
  
Inhibitor
Name:
BDBM50453325
Synonyms:
CHEMBL4205748
Type:
Small organic molecule
Emp. Form.:
C21H25Cl3NO6P
Mol. Mass.:
524.759
SMILES:
Cl.OP(O)(=O)OCCN1CCC2(COc3cc(OCc4c(Cl)cccc4Cl)ccc23)CC1
Structure:
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