Reaction Details  Report a problem with these data
Target
Sphingosine 1-phosphate receptor 5
Ligand
BDBM50453333
Substrate
n/a
Meas. Tech.
ChEMBL_1749910 (CHEMBL4184670)
EC50
32±n/a nM
Citation
  TBA Bioorg Med Chem Lett 28:459-465 (2018) [PubMed]  Article
Target
Name:
Sphingosine 1-phosphate receptor 5
Synonyms:
EDG8 | Endothelial differentiation sphingolipid G-protein-coupled receptor 8 | S1P5 | S1PR5 | S1PR5_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-8
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41796.42
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
398
Sequence:
MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALTASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLDACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRARRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSLLNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSFSGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
  
Inhibitor
Name:
BDBM50453333
Synonyms:
CHEMBL4206573
Type:
Small organic molecule
Emp. Form.:
C24H29Cl2NO4
Mol. Mass.:
466.397
SMILES:
Cl.CCc1cccc(Cl)c1COc1ccc2c(OCC22CCCN(CCC(O)=O)C2)c1
Structure:
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