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Target
D(2) dopamine receptor
Ligand
BDBM50203469
Substrate
n/a
Meas. Tech.
ChEMBL_60379 (CHEMBL672215)
Ki
126±n/a nM
Citation
 Boyfield, I; Brown, TH; Coldwell, MC; Cooper, DG; Hadley, MS; Hagan, JJ; Healy, MA; Johns, A; King, RJ; Middlemiss, DN; Nash, DJ; Riley, GJ; Scott, EE; Smith, SA; Stemp, G Design and synthesis of 2-naphthoate esters as selective dopamine D4 antagonists. J Med Chem 39:1946-8 (1996) [PubMed]  Article
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50203469
Synonyms:
3-Methoxy-naphthalene-2-carboxylic acid (1-benzyl-piperidin-4-ylmethyl)-amide | CHEMBL61248 | N-((1-benzylpiperidin-4-yl)methyl)-3-methoxy-2-naphthamide
Type:
Small organic molecule
Emp. Form.:
C25H28N2O2
Mol. Mass.:
388.502
SMILES:
COc1cc2ccccc2cc1C(=O)NCC1CCN(Cc2ccccc2)CC1
Structure:
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