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Target
Beta-2 adrenergic receptor
Ligand
BDBM50470924
Substrate
n/a
Meas. Tech.
ChEMBL_38477 (CHEMBL650854)
Ki
6.5±n/a nM
Citation
 De Los Angeles, JE; Nikulin, VI; Shams, G; Konkar, AA; Mehta, R; Feller, DR; Miller, DD Iodinated analogs of trimetoquinol as highly potent and selective beta 2-adrenoceptor ligands. J Med Chem 39:3701-11 (1996) [PubMed]  Article
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50470924
Synonyms:
CHEMBL122990
Type:
Small organic molecule
Emp. Form.:
C16H17IN2O2
Mol. Mass.:
396.2229
SMILES:
Nc1ccc(CC2NCCc3cc(O)c(O)cc23)cc1I
Structure:
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