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Target
Beta-2 adrenergic receptor
Ligand
BDBM50093039
Substrate
n/a
Meas. Tech.
ChEMBL_38475 (CHEMBL650853)
Ki
427±n/a nM
Citation
 Zheng, W; Nikulin, VI; Konkar, AA; Vansal, SS; Shams, G; Feller, DR; Miller, DD 2-Amino-4-benzyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridines: novel selective beta3-adrenoceptor agonists. J Med Chem 42:2287-94 (1999) [PubMed]  Article
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50093039
Synonyms:
4-(3,5-Diiodo-4-methoxy-benzyl)-4,5,6,7-tetrahydro-thiazolo[5,4-c]pyridin-2-ylamine | CHEMBL307647
Type:
Small organic molecule
Emp. Form.:
C14H15I2N3OS
Mol. Mass.:
527.162
SMILES:
COc1c(I)cc(CC2NCCc3nc(N)sc23)cc1I
Structure:
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