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Target
Adenosine receptor A2a
Ligand
BDBM50478208
Substrate
n/a
Meas. Tech.
ChEMBL_471613 (CHEMBL941042)
Ki
65±n/a nM
Citation
 Martínez, A; Gutiérrez-de-Terán, H; Brea, J; Raviña, E; Loza, MI; Cadavid, MI; Sanz, F; Vidal, B; Segarra, V; Sotelo, E Synthesis, adenosine receptor binding and 3D-QSAR of 4-substituted 2-(2'-furyl)-1,2,4-triazolo[1,5-a]quinoxalines. Bioorg Med Chem 16:2103-13 (2008) [PubMed]  Article
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50478208
Synonyms:
CHEMBL261346
Type:
Small organic molecule
Emp. Form.:
C19H13N5O
Mol. Mass.:
327.3394
SMILES:
N(c1ccccc1)c1nc2ccccc2n2nc(nc12)-c1ccco1
Structure:
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