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Target
Reverse transcriptase
Ligand
BDBM50478973
Substrate
n/a
Meas. Tech.
ChEMBL_489999 (CHEMBL984662)
Ki
210±n/a nM
Citation
 Marchand, B; White, KL; Ly, JK; Margot, NA; Wang, R; McDermott, M; Miller, MD; Götte, M Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. Antimicrob Agents Chemother 51:2911-9 (2007) [PubMed]  Article
Target
Name:
Reverse transcriptase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
29598.37
Organism:
Human immunodeficiency virus 1
Description:
Q9WKE8
Residue:
254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVN
  
Inhibitor
Name:
BDBM50478973
Synonyms:
CHEMBL1162283
Type:
Small organic molecule
Emp. Form.:
C9H15N5O7P2
Mol. Mass.:
367.1922
SMILES:
C[C@H](Cn1cnc2c(N)ncnc12)OCP(O)(=O)OP(O)(O)=O |r|
Structure:
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