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Target
Reverse transcriptase
Ligand
BDBM50478524
Substrate
n/a
Meas. Tech.
ChEMBL_546666 (CHEMBL1029194)
IC50
14400±n/a nM
Citation
 Beutler, JA; Kashman, Y; Tischler, M; Cardellina, JH; Gray, GN; Currens, MJ; Wall, ME; Wani, MC; Boyd, MR A reinvestigation of Maprounea triterpenes. J Nat Prod 58:1039-46 (1995) [PubMed]  Article
Target
Name:
Reverse transcriptase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
29598.37
Organism:
Human immunodeficiency virus 1
Description:
Q9WKE8
Residue:
254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVN
  
Inhibitor
Name:
BDBM50478524
Synonyms:
CHEMBL450856
Type:
Small organic molecule
Emp. Form.:
C37H52O6
Mol. Mass.:
592.8052
SMILES:
[H][C@@]12CC[C@@]3(C)C4=CC[C@]5(CCC(C)(C)C[C@]5([H])[C@]4(C)CC[C@]3([H])[C@@]1(C)C[C@@H](O)[C@H](OC(=O)c1ccc(O)cc1)C2(C)C)C(O)=O |r,t:6|
Structure:
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