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Target
Reverse transcriptase
Ligand
BDBM50483587
Substrate
n/a
Meas. Tech.
ChEMBL_735834 (CHEMBL1694226)
IC50
54±n/a nM
Citation
 Vadivelan, S; Deeksha, TN; Arun, S; Machiraju, PK; Gundla, R; Sinha, BN; Jagarlapudi, SA Virtual screening studies on HIV-1 reverse transcriptase inhibitors to design potent leads. Eur J Med Chem 46:851-9 (2011) [PubMed]  Article
Target
Name:
Reverse transcriptase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
29598.37
Organism:
Human immunodeficiency virus 1
Description:
Q9WKE8
Residue:
254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVN
  
Inhibitor
Name:
BDBM50483587
Synonyms:
CHEMBL1689312
Type:
Small organic molecule
Emp. Form.:
C19H25NO4S
Mol. Mass.:
363.471
SMILES:
CC(C)C1=C(Sc2cc(C)cc(C)c2)C(COCCO)C(=O)NC1=O |c:3|
Structure:
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