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Target
Reverse transcriptase
Ligand
BDBM50484331
Substrate
n/a
Meas. Tech.
ChEMBL_771986 (CHEMBL1837306)
Ki
1700±n/a nM
Citation
 Novikov, MS; Ivanova, ON; Ivanov, AV; Ozerov, AA; Valuev-Elliston, VT; Temburnikar, K; Gurskaya, GV; Kochetkov, SN; Pannecouque, C; Balzarini, J; Seley-Radtke, KL 1-[2-(2-Benzoyl- and 2-benzylphenoxy)ethyl]uracils as potent anti-HIV-1 agents. Bioorg Med Chem 19:5794-802 (2011) [PubMed]  Article
Target
Name:
Reverse transcriptase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
29598.37
Organism:
Human immunodeficiency virus 1
Description:
Q9WKE8
Residue:
254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVN
  
Inhibitor
Name:
BDBM50484331
Synonyms:
CHEMBL1835508
Type:
Small organic molecule
Emp. Form.:
C21H19BrN2O4
Mol. Mass.:
443.291
SMILES:
Cc1cc(C)cc(c1)C(=O)c1cc(Br)ccc1OCCn1ccc(=O)[nH]c1=O
Structure:
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