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Target
Voltage-dependent L-type calcium channel subunit alpha-1C
Ligand
BDBM50486516
Substrate
n/a
Meas. Tech.
ChEMBL_902802 (CHEMBL3061541)
IC50
4710±n/a nM
Citation
  TBA Med Chem Res 21:284-292 (2012)    Article
Target
Name:
Voltage-dependent L-type calcium channel subunit alpha-1C
Synonyms:
CAC1C_CAVPO | CACH2 | CACH2 | CACN2 | CACNA1C | CACNL1A1 | CCHL1A1 | Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle | Voltage-dependent L-type calcium channel subunit alpha-1C | Voltage-gated calcium channel subunit alpha Cav1.2
Type:
PROTEIN
Mol. Mass.:
19518.62
Organism:
Cavia porcellus
Description:
ChEMBL_106600
Residue:
169
Sequence:
FQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKRAPESEPSNSTEGETPCGSSFAVFY
  
Inhibitor
Name:
BDBM50486516
Synonyms:
CHEMBL2235640
Type:
Small organic molecule
Emp. Form.:
C28H25NO6
Mol. Mass.:
471.5012
SMILES:
COC(=O)C1=C(C)NC(C)=C(C1c1ccc(cc1)-c1cc(=O)cc(o1)-c1ccccc1)C(=O)OC |c:4,9|
Structure:
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