Reaction Details  Report a problem with these data
Target
Adenosine deaminase
Ligand
BDBM50029651
Substrate
n/a
Meas. Tech.
ChEMBL_30934 (CHEMBL647743)
Ki
18200±n/a nM
Citation
 Hakimelahi, GH; Moosavi-Movahedi, AA; Sadeghi, MM; Tsay, SC; Hwu, JR Design, synthesis, and structure-activity relationship of novel dinucleotide analogs as agents against herpes and human immunodeficiency viruses. J Med Chem 38:4648-59 (1995) [PubMed]
Target
Name:
Adenosine deaminase
Synonyms:
ADA | ADA_BOVIN | Adenosine aminohydrolase
Type:
Enzyme
Mol. Mass.:
40910.44
Organism:
Bos taurus (bovine)
Description:
n/a
Residue:
363
Sequence:
MAQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPEFLAKFDYYMPAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAIDLAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGYHTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIFKSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPASAEQCL
  
Inhibitor
Name:
BDBM50029651
Synonyms:
CHEMBL143926 | [2-(6-Amino-purin-9-ylmethoxy)-ethyl]-phosphonic acid
Type:
Small organic molecule
Emp. Form.:
C8H12N5O4P
Mol. Mass.:
273.1857
SMILES:
Nc1ncnc2n(COCCP(O)(O)=O)cnc12
Structure:
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