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Target
Histamine H3 receptor
Ligand
BDBM50034713
Substrate
n/a
Meas. Tech.
ChEMBL_85848 (CHEMBL693575)
Ki
>2000±n/a nM
Citation
 Shih, NY; Lupo, AT; Aslanian, R; Orlando, S; Piwinski, JJ; Green, MJ; Ganguly, AK; Clark, MA; Tozzi, S; Kreutner, W A novel pyrrolidine analog of histamine as a potent, highly selective histamine H3 receptor agonist. J Med Chem 38:1593-9 (1995) [PubMed]
Target
Name:
Histamine H3 receptor
Synonyms:
HISTAMINE H3 | HRH3 | HRH3_CAVPO | Histamine H3 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
48753.61
Organism:
GUINEA PIG
Description:
HISTAMINE H3 HRH3 GUINEA PIG::Q9JI35
Residue:
445
Sequence:
MERAPPDGLMNASGALAGEAAAAAGGARTFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGVFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTSSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMVLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGAREAGPDPLPEAQSSPPQPPPGCWGCWPKGQGESMPLHRYGVGEAGPGAEAGEAALGGGSGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHSSLEHCWK
  
Inhibitor
Name:
BDBM50034713
Synonyms:
(1S,2S)-2-(1H-Imidazol-4-yl)-1-methyl-cyclohexylamine | CHEMBL37568
Type:
Small organic molecule
Emp. Form.:
C10H17N3
Mol. Mass.:
179.2621
SMILES:
C[C@]1(N)CCCC[C@@H]1c1cnc[nH]1
Structure:
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