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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50035989
Substrate
n/a
Meas. Tech.
ChEMBL_202062 (CHEMBL813145)
Ki
400±n/a nM
Citation
 Kiesewetter, DO; Lee, J; Lang, L; Park, SG; Paik, CH; Eckelman, WC Preparation of 18F-labeled muscarinic agonist with M2 selectivity. J Med Chem 38:5-8 (1995) [PubMed]
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25266.54
Organism:
RAT
Description:
Q9R0C9
Residue:
223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50035989
Synonyms:
1-Methyl-4-(4-propylsulfanyl-[1,2,5]thiadiazol-3-yl)-1,2,3,6-tetrahydro-pyridine | CHEMBL167932
Type:
Small organic molecule
Emp. Form.:
C11H17N3S2
Mol. Mass.:
255.403
SMILES:
CCCSc1nsnc1C1=CCN(C)CC1 |t:10|
Structure:
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