Reaction Details  Report a problem with these data
Target
5-hydroxytryptamine receptor 7
Ligand
BDBM50492860
Substrate
n/a
Meas. Tech.
ChEMBL_975302 (CHEMBL2416371)
Ki
9.7±n/a nM
Citation
 Shimoda, Y; Yui, J; Xie, L; Fujinaga, M; Yamasaki, T; Ogawa, M; Nengaki, N; Kumata, K; Hatori, A; Kawamura, K; Zhang, MR Synthesis and evaluation of 1-[2-(4-[(11)C]methoxyphenyl)phenyl]piperazine for imaging of the serotonin 5-HT7 receptor in the rat brain. Bioorg Med Chem 21:5316-22 (2013) [PubMed]  Article
Target
Name:
5-hydroxytryptamine receptor 7
Synonyms:
5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
53573.08
Organism:
Homo sapiens (Human)
Description:
P34969
Residue:
479
Sequence:
MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
  
Inhibitor
Name:
BDBM50492860
Synonyms:
CHEMBL2413451
Type:
Small organic molecule
Emp. Form.:
C24H30N2OS
Mol. Mass.:
393.574
SMILES:
[11CH3]N1C(=O)C2(CCCCCN3CCc4sccc4C3)CCCc3cccc1c23
Structure:
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