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Target
Carbonic anhydrase 7
Ligand
BDBM50153972
Substrate
n/a
Meas. Tech.
ChEMBL_989847 (CHEMBL2446523)
Ki
45±n/a nM
Citation
 Ceruso, M; Vullo, D; Scozzafava, A; Supuran, CT Inhibition of human carbonic anhydrase isoforms I-XIV with sulfonamides incorporating fluorine and 1,3,5-triazine moieties. Bioorg Med Chem 21:6929-36 (2013) [PubMed]  Article
Target
Name:
Carbonic anhydrase 7
Synonyms:
CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:
Enzyme
Mol. Mass.:
29664.11
Organism:
Homo sapiens (Human)
Description:
Human cloned isozyme.
Residue:
264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFRA
  
Inhibitor
Name:
BDBM50153972
Synonyms:
4-(4,6-Bis-methylamino-[1,3,5]triazin-2-ylamino)-benzenesulfonamide | CHEMBL186716
Type:
Small organic molecule
Emp. Form.:
C11H15N7O2S
Mol. Mass.:
309.348
SMILES:
CNc1nc(NC)nc(Nc2ccc(cc2)S(N)(=O)=O)n1
Structure:
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