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Target
Somatostatin receptor type 4
Ligand
BDBM50496016
Substrate
n/a
Meas. Tech.
ChEMBL_1291908 (CHEMBL3124222)
IC50
>1000±n/a nM
Citation
 Tatsi, A; Maina, T; Cescato, R; Waser, B; Krenning, EP; de Jong, M; Cordopatis, P; Reubi, JC; Nock, BA [DOTA]Somatostatin-14 analogs and their (111)In-radioligands: effects of decreasing ring-size on sst1-5 profile, stability and tumor targeting. Eur J Med Chem 73:30-7 (2014) [PubMed]  Article
Target
Name:
Somatostatin receptor type 4
Synonyms:
SOMATOSTATIN SST4 | SS-4-R | SS4-R | SS4R | SSR4_HUMAN | SST4R | SSTR4 | Somatostatin receptor type 4 (SSTR4)
Type:
Enzyme
Mol. Mass.:
42015.38
Organism:
Homo sapiens (Human)
Description:
P31391
Residue:
388
Sequence:
MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF
  
Inhibitor
Name:
BDBM50496016
Synonyms:
CHEMBL3122125
Type:
Small organic molecule
Emp. Form.:
C82H126N22O27S2
Mol. Mass.:
1916.139
SMILES:
[H][C@]1(NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(O)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)CNC(=O)[C@H](C)NC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1)[C@@H](C)O |r|
Structure:
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