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Target
Polyphenol oxidase 2
Ligand
BDBM50292636
Substrate
n/a
Meas. Tech.
ChEMBL_1811784 (CHEMBL4311244)
IC50
610±n/a nM
Citation
 Ishioka, W; Oonuki, S; Iwadate, T; Nihei, KI Resorcinol alkyl glucosides as potent tyrosinase inhibitors. Bioorg Med Chem Lett 29:313-316 (2019) [PubMed]  Article
Target
Name:
Polyphenol oxidase 2
Synonyms:
Monophenol monooxygenase | Monophenol oxidase | PPO2 | PPO2_AGABI | Tyrosinase
Type:
Protein
Mol. Mass.:
63923.66
Organism:
Agaricus bisporus (Common mushroom)
Description:
O42713
Residue:
556
Sequence:
MSLIATVGPTGGVKNRLNIVDFVKNEKFFTLYVRSLELLQAKEQHDYSSFFQLAGIHGLPFTEWAKERPSMNLYKAGYCTHGQVLFPTWHRTYLSVLEQILQGAAIEVAKKFTSNQTDWVQAAQDLRQPYWDWGFELMPPDEVIKNEEVNITNYDGKKISVKNPILRYHFHPIDPSFKPYGDFATWRTTVRNPDRNRREDIPGLIKKMRLEEGQIREKTYNMLKFNDAWERFSNHGISDDQHANSLESVHDDIHVMVGYGKIEGHMDHPFFAAFDPIFWLHHTNVDRLLSLWKAINPDVWVTSGRNRDGTMGIAPNAQINSETPLEPFYQSGDKVWTSASLADTARLGYSYPDFDKLVGGTKELIRDAIDDLIDERYGSKPSSGARNTAFDLLADFKGITKEHKEDLKMYDWTIHVAFKKFELKESFSLLFYFASDGGDYDQENCFVGSINAFRGTAPETCANCQDNENLIQEGFIHLNHYLARDLESFEPQDVHKFLKEKGLSYKLYSRGDKPLTSLSVKIEGRPLHLPPGEHRPKYDHTQARVVFDDVAVHVIN
  
Inhibitor
Name:
BDBM50292636
Synonyms:
4-hexyl resorcinol | ACRISORCIN | CHEMBL443605
Type:
Small organic molecule
Emp. Form.:
C12H18O2
Mol. Mass.:
194.2701
SMILES:
CCCCCCc1ccc(O)cc1O
Structure:
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