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Target
D(3) dopamine receptor
Ligand
BDBM50055811
Substrate
n/a
Meas. Tech.
ChEMBL_62266 (CHEMBL675668)
Ki
289±n/a nM
Citation
 Thurkauf, A; Yuan, J; Chen, X; He, XS; Wasley, JW; Hutchison, A; Woodruff, KH; Meade, R; Hoffman, DC; Donovan, H; Jones-Hertzog, DK 2-Phenyl-4(5)-[[4-(pyrimidin-2-yl)piperazin-1-yl]methyl]imidazole. A highly selective antagonist at cloned human D4 receptors. J Med Chem 40:1-3 (1997) [PubMed]  Article
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50055811
Synonyms:
1-(2-Phenyl-3H-imidazol-4-ylmethyl)-4-pyridin-3-yl-piperazine | CHEMBL321513
Type:
Small organic molecule
Emp. Form.:
C19H21N5
Mol. Mass.:
319.4035
SMILES:
C(N1CCN(CC1)c1cccnc1)c1cnc([nH]1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: