Reaction Details  Report a problem with these data
Target
Melatonin receptor type 1A
Ligand
BDBM50506043
Substrate
n/a
Meas. Tech.
ChEMBL_1824696 (CHEMBL4324460)
Ki
1.4±n/a nM
Citation
 Wang, SY; Shi, XC; Laborda, P Indole-based melatonin analogues: Synthetic approaches and biological activity. Eur J Med Chem 185:0 (2020) [PubMed]  Article
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50506043
Synonyms:
CHEMBL4548591
Type:
Small organic molecule
Emp. Form.:
C14H17BrN2O3
Mol. Mass.:
341.2
SMILES:
CC(=O)NCCc1c(Br)[nH]c2ccc(OCCO)cc12
Structure:
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