Reaction Details  Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50061196
Substrate
n/a
Meas. Tech.
ChEMBL_46985 (CHEMBL872426)
Ki
36±n/a nM
Citation
 Reggio, PH; Wang, T; Brown, AE; Fleming, DN; Seltzman, HH; Griffin, G; Pertwee, RG; Compton, DR; Abood, ME; Martin, BR Importance of the C-1 substituent in classical cannabinoids to CB2 receptor selectivity: synthesis and characterization of a series of O,2-propano-delta 8-tetrahydrocannabinol analogs. J Med Chem 40:3312-8 (1997) [PubMed]  Article
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50061196
Synonyms:
8,8,11-Trimethyl-5-pentyl-3,4,8a,9,10,12a-hexahydro-2H,8H-1,7-dioxa-benzo[c]phenanthrene | CHEMBL114189
Type:
Small organic molecule
Emp. Form.:
C24H34O2
Mol. Mass.:
354.5256
SMILES:
CCCCCc1cc2OC(C)(C)C3CCC(C)=CC3c2c2OCCCc12 |c:16|
Structure:
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