Reaction Details  Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50063204
Substrate
n/a
Meas. Tech.
ChEMBL_29121 (CHEMBL642255)
Ki
43±n/a nM
Citation
 Betti, L; Biagi, G; Giannaccini, G; Giorgi, I; Livi, O; Lucacchini, A; Manera, C; Scartoni, V Novel 3-aralkyl-7-(amino-substituted)-1,2,3-triazolo[4,5-d]pyrimidines with high affinity toward A1 adenosine receptors. J Med Chem 41:668-73 (1998) [PubMed]  Article
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36602.99
Organism:
BOVINE
Description:
ADENOSINE 0 BOVINE::P28190
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYMVYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPVDEDAPAERPDD
  
Inhibitor
Name:
BDBM50063204
Synonyms:
CHEMBL161711 | [3-(2-Chloro-benzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-cyclohexyl-amine
Type:
Small organic molecule
Emp. Form.:
C17H19ClN6
Mol. Mass.:
342.826
SMILES:
Clc1ccccc1Cn1nnc2c(NC3CCCCC3)ncnc12
Structure:
Search PDB for entries with ligand similarity: