Reaction Details  Report a problem with these data
Target
Somatostatin receptor type 4
Ligand
BDBM50064029
Substrate
n/a
Meas. Tech.
ChEMBL_200515 (CHEMBL801019)
Ki
3000±n/a nM
Citation
 Hirschmann, R; Hynes, J; Cichy-Knight, MA; van Rijn, RD; Sprengeler, PA; Spoors, PG; Shakespeare, WC; Pietranico-Cole, S; Barbosa, J; Liu, J; Yao, W; Rohrer, S; Smith, AB Modulation of receptor and receptor subtype affinities using diastereomeric and enantiomeric monosaccharide scaffolds as a means to structural and biological diversity. A new route to ether synthesis. J Med Chem 41:1382-91 (1998) [PubMed]  Article
Target
Name:
Somatostatin receptor type 4
Synonyms:
SOMATOSTATIN SST4 | SS-4-R | SS4-R | SS4R | SSR4_HUMAN | SST4R | SSTR4 | Somatostatin receptor type 4 (SSTR4)
Type:
Enzyme
Mol. Mass.:
42015.38
Organism:
Homo sapiens (Human)
Description:
P31391
Residue:
388
Sequence:
MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF
  
Inhibitor
Name:
BDBM50064029
Synonyms:
5-{(2R,3S,5R,6R)-3-Benzyloxy-5-(1H-imidazol-4-ylmethoxy)-6-[2-(1H-indol-3-yl)-ethoxy]-tetrahydro-pyran-2-ylmethoxy}-pentylamine | CHEMBL28824
Type:
Small organic molecule
Emp. Form.:
C32H42N4O5
Mol. Mass.:
562.6997
SMILES:
NCCCCCOC[C@H]1O[C@@H](OCCc2c[nH]c3ccccc23)[C@@H](C[C@@H]1OCc1ccccc1)OCc1cnc[nH]1
Structure:
Search PDB for entries with ligand similarity: