Reaction Details  Report a problem with these data
Target
Growth hormone secretagogue receptor type 1
Ligand
BDBM50066809
Substrate
n/a
Meas. Tech.
ChEMBL_193174 (CHEMBL798749)
EC50
35±n/a nM
Citation
 Hansen, TK; Ankersen, M; Hansen, BS; Raun, K; Nielsen, KK; Lau, J; Peschke, B; Lundt, BF; Thøgersen, H; Johansen, NL; Madsen, K; Andersen, PH Novel orally active growth hormone secretagogues. J Med Chem 41:3705-14 (1998) [PubMed]  Article
Target
Name:
Growth hormone secretagogue receptor type 1
Synonyms:
GH-releasing peptide receptor | GHRP | GHS-R | GHSR_RAT | Ghrelin receptor | Ghsr | Growth hormone secretagogue receptor type 1
Type:
PROTEIN
Mol. Mass.:
40970.19
Organism:
Rattus norvegicus
Description:
ChEMBL_11556
Residue:
364
Sequence:
MWNATPSEEPEPNVTLDLDWDASPGNDSLPDELLPLFPAPLLAGVTATCVALFVVGISGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVILVIWAVAFCSAGPIFVLVGVEHENGTDPRDTNECRATEFAVRSGLLTVMVWVSSVFFFLPVFCLTVLYSLIGRKLWRRRGDAAVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFKLLGFESFSQRKLSTLKDESSRAWTKSSINT
  
Inhibitor
Name:
BDBM50066809
Synonyms:
(E)-5-Amino-5-methyl-hex-2-enoic acid {(R)-2-benzo[b]thiophen-3-yl-1-[methyl-((R)-1-methylcarbamoyl-2-phenyl-ethyl)-carbamoyl]-ethyl}-methyl-amide | CHEMBL121960
Type:
Small organic molecule
Emp. Form.:
C30H38N4O3S
Mol. Mass.:
534.713
SMILES:
CNC(=O)[C@@H](Cc1ccccc1)N(C)C(=O)[C@@H](Cc1csc2ccccc12)N(C)C(=O)\C=C\CC(C)(C)N
Structure:
Search PDB for entries with ligand similarity: