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Target
Growth hormone secretagogue receptor type 1
Ligand
BDBM50066814
Substrate
n/a
Meas. Tech.
ChEMBL_193174 (CHEMBL798749)
EC50
6±n/a nM
Citation
 Hansen, TK; Ankersen, M; Hansen, BS; Raun, K; Nielsen, KK; Lau, J; Peschke, B; Lundt, BF; Thøgersen, H; Johansen, NL; Madsen, K; Andersen, PH Novel orally active growth hormone secretagogues. J Med Chem 41:3705-14 (1998) [PubMed]  Article
Target
Name:
Growth hormone secretagogue receptor type 1
Synonyms:
GH-releasing peptide receptor | GHRP | GHS-R | GHSR_RAT | Ghrelin receptor | Ghsr | Growth hormone secretagogue receptor type 1
Type:
PROTEIN
Mol. Mass.:
40970.19
Organism:
Rattus norvegicus
Description:
ChEMBL_11556
Residue:
364
Sequence:
MWNATPSEEPEPNVTLDLDWDASPGNDSLPDELLPLFPAPLLAGVTATCVALFVVGISGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVILVIWAVAFCSAGPIFVLVGVEHENGTDPRDTNECRATEFAVRSGLLTVMVWVSSVFFFLPVFCLTVLYSLIGRKLWRRRGDAAVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFKLLGFESFSQRKLSTLKDESSRAWTKSSINT
  
Inhibitor
Name:
BDBM50066814
Synonyms:
(E)-5-Amino-5-methyl-hex-2-enoic acid [(R)-1-{[(R)-2-(4-fluoro-phenyl)-1-((R)-2-hydroxy-propylcarbamoyl)-ethyl]-methyl-carbamoyl}-2-(4-phenyl-cyclohexa-1,5-dienyl)-ethyl]-methyl-amide | CHEMBL331303
Type:
Small organic molecule
Emp. Form.:
C36H47FN4O4
Mol. Mass.:
618.7812
SMILES:
C[C@@H](O)CNC(=O)[C@@H](Cc1ccc(F)cc1)N(C)C(=O)[C@@H](CC1=CCC(C=C1)c1ccccc1)N(C)C(=O)\C=C\CC(C)(C)N |c:27,t:23|
Structure:
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