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Target
Growth hormone secretagogue receptor type 1
Ligand
BDBM50066825
Substrate
n/a
Meas. Tech.
ChEMBL_193174 (CHEMBL798749)
EC50
1.5±n/a nM
Citation
 Hansen, TK; Ankersen, M; Hansen, BS; Raun, K; Nielsen, KK; Lau, J; Peschke, B; Lundt, BF; Thøgersen, H; Johansen, NL; Madsen, K; Andersen, PH Novel orally active growth hormone secretagogues. J Med Chem 41:3705-14 (1998) [PubMed]  Article
Target
Name:
Growth hormone secretagogue receptor type 1
Synonyms:
GH-releasing peptide receptor | GHRP | GHS-R | GHSR_RAT | Ghrelin receptor | Ghsr | Growth hormone secretagogue receptor type 1
Type:
PROTEIN
Mol. Mass.:
40970.19
Organism:
Rattus norvegicus
Description:
ChEMBL_11556
Residue:
364
Sequence:
MWNATPSEEPEPNVTLDLDWDASPGNDSLPDELLPLFPAPLLAGVTATCVALFVVGISGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVILVIWAVAFCSAGPIFVLVGVEHENGTDPRDTNECRATEFAVRSGLLTVMVWVSSVFFFLPVFCLTVLYSLIGRKLWRRRGDAAVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFKLLGFESFSQRKLSTLKDESSRAWTKSSINT
  
Inhibitor
Name:
BDBM50066825
Synonyms:
(E)-5-Amino-5-methyl-hex-2-enoic acid [(R)-1-{[(R)-1-((S)-2-hydroxy-propylcarbamoyl)-2-thiophen-2-yl-ethyl]-methyl-carbamoyl}-2-(4-phenyl-cyclohexa-1,5-dienyl)-ethyl]-methyl-amide | CHEMBL122939
Type:
Small organic molecule
Emp. Form.:
C34H46N4O4S
Mol. Mass.:
606.818
SMILES:
C[C@H](O)CNC(=O)[C@@H](Cc1cccs1)N(C)C(=O)[C@@H](CC1=CCC(C=C1)c1ccccc1)N(C)C(=O)\C=C\CC(C)(C)N |c:25,t:21|
Structure:
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