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Target
Serine protease 1
Ligand
BDBM50070783
Substrate
n/a
Meas. Tech.
ChEBML_212505
Ki
16200±n/a nM
Citation
 Lee, K; Hwang, SY; Yun, M; Kim, DS Potent and efficacious thienylamidine-incorporated thrombin inhibitors. Bioorg Med Chem Lett 8:1683-6 (1999) [PubMed]
Target
Name:
Serine protease 1
Synonyms:
Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bos taurus (bovine)
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
  
Inhibitor
Name:
BDBM50070783
Synonyms:
(S)-3-(4-Carbamimidoyl-phenyl)-N-cyclopentyl-N-methyl-2-(naphthalene-2-sulfonylamino)-propionamide | 1N-cyclopentyl-1N-methyl-3-[4-amino(imino)methylphenyl]-2-(2-naphthylsulfonamido)-(2S)-propanamide | CHEMBL7656
Type:
Small organic molecule
Emp. Form.:
C26H30N4O3S
Mol. Mass.:
478.606
SMILES:
CN(C1CCCC1)C(=O)[C@H](Cc1ccc(cc1)C(N)=N)NS(=O)(=O)c1ccc2ccccc2c1
Structure:
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