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Target
Reverse transcriptase
Ligand
BDBM50516932
Substrate
n/a
Meas. Tech.
ChEMBL_1867169 (CHEMBL4368144)
IC50
11000±n/a nM
Citation
 Garg, V; Maurya, RK; Thanikachalam, PV; Bansal, G; Monga, V An insight into the medicinal perspective of synthetic analogs of indole: A review. Eur J Med Chem 180:562-612 (2019) [PubMed]  Article
Target
Name:
Reverse transcriptase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
29598.37
Organism:
Human immunodeficiency virus 1
Description:
Q9WKE8
Residue:
254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVN
  
Inhibitor
Name:
BDBM50516932
Synonyms:
CHEMBL1652111 | IDX899
Type:
Small organic molecule
Emp. Form.:
C20H17ClN3O3P
Mol. Mass.:
413.794
SMILES:
COP(=O)(c1c([nH]c2ccc(Cl)cc12)C(N)=O)c1cc(C)cc(\C=C\C#N)c1
Structure:
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