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Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50521127
Substrate
n/a
Meas. Tech.
ChEMBL_1883037 (CHEMBL4384536)
IC50
3700±n/a nM
Citation
 Lai, MJ; Ojha, R; Lin, MH; Liu, YM; Lee, HY; Lin, TE; Hsu, KC; Chang, CY; Chen, MC; Nepali, K; Chang, JY; Liou, JP 1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase. Eur J Med Chem 162:612-630 (2019) [PubMed]  Article
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50521127
Synonyms:
CHEMBL4439839
Type:
Small organic molecule
Emp. Form.:
C28H25FN4O3S
Mol. Mass.:
516.587
SMILES:
Nc1ccccc1NC(=O)c1ccc(CNc2cccc3CCN(c23)S(=O)(=O)c2ccc(F)cc2)cc1
Structure:
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