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Target
TYR_PHOSPHATASE_2 domain-containing protein
Ligand
BDBM50523081
Substrate
n/a
Meas. Tech.
ChEMBL_1888916 (CHEMBL4390593)
IC50
>50000±n/a nM
Citation
 Cai, R; Jiang, H; Mo, Y; Guo, H; Li, C; Long, Y; Zang, Z; She, Z Ophiobolin-Type Sesterterpenoids from the Mangrove Endophytic Fungus  J Nat Prod 82:2268-2278 (2019) [PubMed]  Article
Target
Name:
TYR_PHOSPHATASE_2 domain-containing protein
Synonyms:
(PROTEIN-TYROSINE-PHOSPHATASE) (PTPase) | MPtpB | PHOSPHOTYROSINE PROTEIN PHOSPHATASE PTPB | Phosphotyrosine protein phosphatase | Phosphotyrosine-protein phosphatase PTPB | Protein Tyrosine Phosphatase PTPB
Type:
Hydrolase
Mol. Mass.:
30152.45
Organism:
Mycobacterium tuberculosis
Description:
n/a
Residue:
276
Sequence:
MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSINDAATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLAAARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG
  
Inhibitor
Name:
BDBM50523081
Synonyms:
CHEMBL4440954
Type:
Small organic molecule
Emp. Form.:
C25H38O3
Mol. Mass.:
386.5674
SMILES:
[H][C@@]1([#6]-[#6][C@]2([#6])[#6][C@@]3([H])[C@]4([H])\[#6](-[#6]-[#8][C@]4([#8])[#6][C@@]3([#6])[#8])=[#6]/[#6][C@@]12[H])[#6@@H](-[#6])\[#6]=[#6]/[#6]=[#6](/[#6])-[#6] |r,c:21|
Structure:
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