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Target
D(2) dopamine receptor
Ligand
BDBM50080049
Substrate
n/a
Meas. Tech.
ChEMBL_58759 (CHEMBL669147)
Ki
339±n/a nM
Citation
 Höök, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Derivatives of (R)-2-amino-5-methoxytetralin: antagonists and inverse agonists at the dopamine D2A receptor. Bioorg Med Chem Lett 9:2167-72 (1999) [PubMed]
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50080049
Synonyms:
((R)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-thiophen-2-ylmethyl-amine | CHEMBL69706
Type:
Small organic molecule
Emp. Form.:
C19H25NOS
Mol. Mass.:
315.473
SMILES:
CCCN(Cc1cccs1)[C@@H]1CCc2c(C1)cccc2OC
Structure:
Search PDB for entries with ligand similarity: