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Target
Adenosine receptor A3
Ligand
BDBM50527843
Substrate
n/a
Meas. Tech.
ChEMBL_1903807 (CHEMBL4406029)
Ki
531±n/a nM
Citation
 Tosh, DK; Salmaso, V; Rao, H; Bitant, A; Fisher, CL; Lieberman, DI; Vorbrüggen, H; Reitman, ML; Gavrilova, O; Gao, ZG; Auchampach, JA; Jacobson, KA Truncated (N)-Methanocarba Nucleosides as Partial Agonists at Mouse and Human A J Med Chem 63:4334-4348 (2020) [PubMed]  Article
Target
Name:
Adenosine receptor A3
Synonyms:
A3AR | AA3R_MOUSE | Adenosine A3 receptor | Adora3 | Gpcr2
Type:
PROTEIN
Mol. Mass.:
36460.91
Organism:
Mus musculus
Description:
ChEMBL_1515686
Residue:
319
Sequence:
MEADNTTETDWLNITYITMEAAIGLCAVVGNMLVIWVVKLNPTLRTTTVYFIVSLALADIAVGVLVIPLAIAVSLQVKMHFYACLFMSCVLLIFTHASIMSLLAIAVHRYLRVKLTVRYRTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKATLASSQNSSTLLCHFRSVVSLDYMVFFSFITWILVPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFDVKIPDVAMCLGILLSHANSMMNPIVYACKIKKFKETYFLILRAVRLCQTSDSLDSNMEQTTE
  
Inhibitor
Name:
BDBM50527843
Synonyms:
CHEMBL4537118
Type:
Small organic molecule
Emp. Form.:
C25H21Cl2N5O2S
Mol. Mass.:
526.438
SMILES:
[H][C@@]12C[C@]1([H])[C@H]([C@H](O)[C@@H]2O)n1cnc2c(NCCc3cccc(Cl)c3)nc(nc12)C#Cc1ccc(Cl)s1 |r|
Structure:
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