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Target
Histone deacetylase 2b
Ligand
BDBM50082660
Substrate
n/a
Meas. Tech.
ChEMBL_87885 (CHEMBL698803)
IC50
100±n/a nM
Citation
 Jung, M; Brosch, G; Kölle, D; Scherf, H; Gerhäuser, C; Loidl, P Amide analogues of trichostatin A as inhibitors of histone deacetylase and inducers of terminal cell differentiation. J Med Chem 42:4669-79 (1999) [PubMed]
Target
Name:
Histone deacetylase 2b
Synonyms:
Histone deacetylase HD2
Type:
PROTEIN
Mol. Mass.:
30785.07
Organism:
Zea mays
Description:
ChEMBL_87549
Residue:
286
Sequence:
MEVGGQEVKPGATVSCKVGDGLVIHLSQAALGESKKASENAILSVNIDDKKLVLGTLSVEKHPQISCDLVFDKDFELPHNSKTRSVFFRGYKSPVPLFESNSGEDSSDEELKTDQIPLQNNEIKISAAKVPAKDDDDDVFIILAMMMMIYSSDDDDDDFTTSDSDNEMSEEDDSSDEDEMSEEDDSSDEDEMSGGADPSDDSSDESGSEHTSAPKKTDVVVGKKRAIKAEAPYGKKAKSEQSSQKTGDKASTSHPAKQSIKTPADKSRKTPTADKKSPKSGSHGCK
  
Inhibitor
Name:
BDBM50082660
Synonyms:
Biphenyl-4-carboxylic acid (5-hydroxycarbamoyl-pentyl)-amide | CHEMBL143327 | N-[6-(Hydroxyamino)-6-oxohexyl][1,10-biphenyl]-4-carboxamide
Type:
Small organic molecule
Emp. Form.:
C19H22N2O3
Mol. Mass.:
326.3896
SMILES:
ONC(=O)CCCCCNC(=O)c1ccc(cc1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: