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Target
Nonstructural protein 3
Ligand
BDBM50528549
Substrate
n/a
Meas. Tech.
ChEMBL_1905425 (CHEMBL4407783)
IC50
9190±n/a nM
Citation
 Rassias, G; Zogali, V; Swarbrick, CMD; Ki Chan, KW; Chan, SA; Gwee, CP; Wang, S; Kaplanai, E; Canko, A; Kiousis, D; Lescar, J; Luo, D; Matsoukas, MT; Vasudevan, SG Cell-active carbazole derivatives as inhibitors of the zika virus protease. Eur J Med Chem 180:536-545 (2019) [PubMed]  Article
Target
Name:
Nonstructural protein 3
Synonyms:
Genome polyprotein | NS3
Type:
PROTEIN
Mol. Mass.:
7653.58
Organism:
Zika virus
Description:
ChEMBL_119671
Residue:
66
Sequence:
AETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADKVAAIEGEFKLRTEQRKTFVELMKRGDLPV
  
Inhibitor
Name:
BDBM50528549
Synonyms:
CHEMBL4457232
Type:
Small organic molecule
Emp. Form.:
C26H20BrN5O2S
Mol. Mass.:
546.438
SMILES:
NC(=N)c1cccc(c1)-c1ccc2n(c3ccc(Br)cc3c2c1)S(=O)(=O)c1cccc(c1)C(N)=N
Structure:
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