Reaction Details  Report a problem with these data
Target
Superoxide dismutase [Cu-Zn]
Ligand
BDBM50529854
Substrate
n/a
Meas. Tech.
ChEMBL_1910488 (CHEMBL4412934)
IC50
>100000±n/a nM
Citation
 Martín-Escolano, R; Molina-Carreño, D; Delgado-Pinar, E; Martin-Montes, Á; Clares, MP; Medina-Carmona, E; Pitarch-Jarque, J; Martín-Escolano, J; Rosales, MJ; García-España, E; Sánchez-Moreno, M; Marín, C New polyamine drugs as more effective antichagas agents than benznidazole in both the acute and chronic phases. Eur J Med Chem 164:27-46 (2019) [PubMed]  Article
Target
Name:
Superoxide dismutase [Cu-Zn]
Synonyms:
SOD1 | SODC_HUMAN | Superoxide dismutase
Type:
PROTEIN
Mol. Mass.:
15933.55
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1444880
Residue:
154
Sequence:
MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ
  
Inhibitor
Name:
BDBM50529854
Synonyms:
CHEMBL4451604
Type:
Small organic molecule
Emp. Form.:
C20H31Cl3N4
Mol. Mass.:
433.846
SMILES:
Cl.Cl.Cl.NCCN(CCN)CCNCc1ccc-2c(Cc3ccccc-23)c1
Structure:
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