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Target
D(1A) dopamine receptor
Ligand
BDBM50017041
Substrate
n/a
Meas. Tech.
ChEBML_58797
Ki
248800±n/a nM
Citation
 Kawai, H; Kotake, Y; Ohta, S Inhibition of dopamine receptors by endogenous amines: binding to striatal receptors and pharmacological effects on locomotor activity. Bioorg Med Chem Lett 10:1669-71 (2000) [PubMed]
Target
Name:
D(1A) dopamine receptor
Synonyms:
DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49429.75
Organism:
RAT
Description:
P18901
Residue:
446
Sequence:
MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
  
Inhibitor
Name:
BDBM50017041
Synonyms:
(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline | 1,2,3,4-Tetrahydro-1-(phenylmethyl)isoquinoline | 1BnTIQ | CHEMBL21640 | rac-(1R)-1-benzyl-1,2,3,4-tetrahydroisoquinoline
Type:
Small organic molecule
Emp. Form.:
C16H17N
Mol. Mass.:
223.3129
SMILES:
C(C1NCCc2ccccc12)c1ccccc1
Structure:
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