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Target
Protein tyrosine phosphatase type IVA 3
Ligand
BDBM50535760
Substrate
n/a
Meas. Tech.
ChEMBL_1931297 (CHEMBL4434548)
IC50
15400±n/a nM
Citation
 Tasker, NR; Rastelli, EJ; Burnett, JC; Sharlow, ER; Lazo, JS; Wipf, P Tapping the therapeutic potential of protein tyrosine phosphatase 4A with small molecule inhibitors. Bioorg Med Chem Lett 29:2008-2015 (2019) [PubMed]  Article
Target
Name:
Protein tyrosine phosphatase type IVA 3
Synonyms:
PRL3 | PTP4A3 | Protein-tyrosine phosphatase 4A3 | TP4A3_HUMAN
Type:
PROTEIN
Mol. Mass.:
19546.22
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1461022
Residue:
173
Sequence:
MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
  
Inhibitor
Name:
BDBM50535760
Synonyms:
CHEMBL4466901
Type:
Small organic molecule
Emp. Form.:
C21H14ClN3O3S
Mol. Mass.:
423.872
SMILES:
OC(=O)c1cccc(c1)-n1cccc1\C=C1\NC(=S)N(C1=O)c1cccc(Cl)c1
Structure:
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