Reaction Details  Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50536982
Substrate
n/a
Meas. Tech.
ChEMBL_1935276 (CHEMBL4481035)
Ki
33±n/a nM
Citation
 Intagliata, S; Alsharif, WF; Mesangeau, C; Fazio, N; Seminerio, M; Xu, YT; Matsumoto, RR; McCurdy, CR Benzimidazolone-based selective ? Eur J Med Chem 165:250-257 (2019) [PubMed]  Article
Target
Name:
Sigma intracellular receptor 2
Synonyms:
S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20953.88
Organism:
Rattus norvegicus (Rat)
Description:
Q5U3Y7
Residue:
176
Sequence:
MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILFEDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
  
Inhibitor
Name:
BDBM50536982
Synonyms:
CHEMBL4525954
Type:
Small organic molecule
Emp. Form.:
C33H47FN4O2
Mol. Mass.:
550.7503
SMILES:
CCCCCCCCCCn1c2cc(ccc2n(CCCCN2CCN(CC2)c2ccc(F)cc2)c1=O)C(C)=O
Structure:
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